Cytophotometric studies of cell populations

Technologic advances in the recording of digitized imagery have made the study of large cell populations by image analytical methods feasible. Computed image information provides quantitative, and novel, information that allows an exact measurement of minute changes in the chromatin distribution of...

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Bibliographic Details
Published in:Cell biophysics Vol. 2; no. 4; p. 339
Main Authors: Bartels, P H, Olson, G B, Lockart, R, Wied, G L
Format: Journal Article
Language:English
Published: United States 01.12.1980
Subjects:
Animals
Cell Line
Cell Nucleus - ultrastructure
Chromatin - analysis
Computers
Cytological Techniques
Humans
Interferons - pharmacology
Lymphocyte Activation
Spectrophotometry
ISSN:0163-4992
Online Access:Get more information
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Summary:Technologic advances in the recording of digitized imagery have made the study of large cell populations by image analytical methods feasible. Computed image information provides quantitative, and novel, information that allows an exact measurement of minute changes in the chromatin distribution of cell nuclei, and the detection of subpopulations of cells or changes in the functional state of the cells. The sensitivity of the detection exceeds that of human observers; the specificity of the measured changes must be the subject of basic cell biologic research.
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ISSN:0163-4992
DOI:10.1007/BF02785098