High feasibility of salivary therapeutic drug monitoring in linezolid, but lower feasibility in tedizolid: a single-dose study in healthy subjects and a monocentric prospective exploratory study in patients who received linezolid

Salivary therapeutic drug monitoring (TDM) offers the potential to reduce the risks, burden, time and costs of blood-based TDM, but its feasibility for use with oxazolidinone antibiotics and the influence of food intake remain unknown. We conducted a healthy subject study with 12 healthy participant...

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