A path integral approach for allele frequency dynamics under polygenic selection

Many phenotypic traits have a polygenic genetic basis, making it challenging to learn their genetic architectures and predict individual phenotypes. One promising avenue to resolve the genetic basis of complex traits is through evolve-and-resequence (E&R) experiments, in which laboratory populat...

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Bibliographic Details

Published in:	Genetics (Austin) Vol. 229; no. 1; p. 1
Main Authors:	Anderson, Nathan W, Kirk, Lloyd, Schraiber, Joshua G, Ragsdale, Aaron P
Format:	Journal Article
Language:	English
Published:	United States 08.01.2025
Subjects:	Alleles Gene Frequency Genetic Drift Models, Genetic Multifactorial Inheritance Phenotype Selection, Genetic evolve and resequence polygenic selection diffusion approximation transition density
ISSN:	1943-2631, 1943-2631
Online Access:	Get more information
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