Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy

Diabetic nephropathy remains an area of high unmet medical need, with current therapies that slow down, but do not prevent, the progression of disease. A reduced phosphorylation state of adenosine monophosphate-activated protein kinase (AMPK) has been correlated with diminished kidney function in bo...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics Jg. 361; H. 2; S. 303
Hauptverfasser:	Salatto, Christopher T, Miller, Russell A, Cameron, Kimberly O, Cokorinos, Emily, Reyes, Allan, Ward, Jessica, Calabrese, Matthew F, Kurumbail, Ravi G, Rajamohan, Francis, Kalgutkar, Amit S, Tess, David A, Shavnya, Andre, Genung, Nathan E, Edmonds, David J, Jatkar, Aditi, Maciejewski, Benjamin S, Amaro, Marina, Gandhok, Harmeet, Monetti, Mara, Cialdea, Katherine, Bollinger, Eliza, Kreeger, John M, Coskran, Timothy M, Opsahl, Alan C, Boucher, Germaine G, Birnbaum, Morris J, DaSilva-Jardine, Paul, Rolph, Tim
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	01.05.2017
ISSN:	1521-0103, 1521-0103
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