Safety and Clinical Effects of Mesenchymal Stem Cells Secreting Neurotrophic Factor Transplantation in Patients With Amyotrophic Lateral Sclerosis: Results of Phase 1/2 and 2a Clinical Trials

Preclinical studies have shown that neurotrophic growth factors (NTFs) extend the survival of motor neurons in amyotrophic lateral sclerosis (ALS) and that the combined delivery of these neurotrophic factors has a strong synergistic effect. We have developed a culture-based method for inducing mesen...

Celý popis

Podrobná bibliografie

Vydáno v:	JAMA neurology Ročník 73; číslo 3; s. 337
Hlavní autoři:	Petrou, Panayiota, Gothelf, Yael, Argov, Zohar, Gotkine, Marc, Levy, Yossef S, Kassis, Ibrahim, Vaknin-Dembinsky, Adi, Ben-Hur, Tamir, Offen, Daniel, Abramsky, Oded, Melamed, Eldad, Karussis, Dimitrios
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.03.2016
Témata:	Adult Aged Amyotrophic Lateral Sclerosis - therapy Female Follow-Up Studies Humans Male Mesenchymal Stem Cell Transplantation - adverse effects Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stromal Cells - secretion Middle Aged Nerve Growth Factors - secretion Outcome Assessment (Health Care) Transplantation, Autologous Young Adult
ISSN:	2168-6157, 2168-6157
On-line přístup:	Zjistit podrobnosti o přístupu
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!