Novel mutation of the cyclin-dependent kinase 4 gene in a Chinese patient with intimal sarcoma of the pulmonary artery

The long arm of human chromosome 12 contains a region that has been found to be amplified in a number of different tumors, including osteosarcomas and soft tissue sarcomas. There are more than 5 genes located in this area such as CDK2, CDK4, WNT1, MDM2 and WNTIOb. CDK4 gene consists of eight exons,...

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Bibliographic Details
Published in:	Chinese medical journal Vol. 122; no. 9; pp. 1107 - 1109
Main Authors:	Gao, Feng, Liu, Qi-cai, Wang, Mi, Wang, Zhi-qiang, Huang, Yi, Zhou, Xiao-hui, Zhang, Sheng
Format:	Journal Article
Language:	English
Published:	China Department of Gene Diagnosis First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian 350005, China%Department of Neurology First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian 350005, China%Department of Chemistry First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian 350005, China%Department of Laboratory Medicine First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian 350005, China 05.05.2009 Department of Pathology First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian 350005, China%Department of Laboratory Medicine First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian 350005, China
Subjects:	12号染色体 CDK4基因 Cyclin-Dependent Kinase 4 - genetics Exons - genetics Humans Magnetic Resonance Imaging Mutation - genetics Polymerase Chain Reaction Polymorphism, Genetic - genetics Pulmonary Artery - metabolism Pulmonary Artery - pathology Sarcoma - genetics 第8外显子细胞周期蛋白依赖性激酶4 肺动脉软组织肉瘤 CDK4 gene pulmonary artery clinical character intimal sarcoma
ISSN:	0366-6999, 2542-5641, 2542-5641
Online Access:	Get full text
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