Long-term follow up of interventional therapy of secundum atrial septal defect

Background The percutaneous transcatheter closure of secundum atrial septal defect （ASD） is increasingly a widespread alternative to surgical closure.The aim of this study was to assess long-term results of percutaneous closure of secundum-type atrial septal defect （ASD Ⅱ）.Methods Between January 20...

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Published in:Chinese medical journal Vol. 125; no. 1; pp. 149 - 152
Main Authors: Yuan, Yi-Qiang, Huang, Qiong, Yu, Li, Wang, Rui-Min, Zhao, Yu-Jie, Guo, Ying-Xian, Sun, Jun-Hua, Niu, Si-Quan, Sun, Yun, Yang, Xing-Ming, Mao, You-Lin
Format: Journal Article
Language:English
Published: China Department of Cardiology, Zhnengzhou Cardiovascular Hospital, Zhengzhou, Henan 450016, China 05.01.2012
Subjects:
Adolescent
Adult
Child
Child, Preschool
Female
Follow-Up Studies
Heart Septal Defects, Atrial - diagnostic imaging
Heart Septal Defects, Atrial - surgery
Humans
Male
Middle Aged
Ultrasonography
Young Adult
介入治疗
右心室
孔型
左心室
房间
继发
缺损
超声心动图
congenital heart disease
atrial
interventional
heart septal defects
ISSN:0366-6999, 2542-5641, 2542-5641
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Summary:Background The percutaneous transcatheter closure of secundum atrial septal defect （ASD） is increasingly a widespread alternative to surgical closure.The aim of this study was to assess long-term results of percutaneous closure of secundum-type atrial septal defect （ASD Ⅱ）.Methods Between January 2001 and December 2005,61 patients underwent a successful percutaneous closure of ASD Ⅱ; including 25 male and 36 female.All were included in the patient study and were followed up to monitor by electrocardiogram and echocardiography,at intervals of 3 days,3 months,6 months,1 year,2 years,and 5 years after operation.Results Three days after percutaneous transcatheter septal closure （PTSC）,the right atrium diameter,right ventricular end-diastolic left-right diameter and right ventricutar end-diastolic volume （RVEDV） decreased significantly （P 〈0.05）.Right ventricular end-diastolic anteroposterior diameter （RVEDD）,right ventricular end-systolic volume （RVESV） and right ventricular ejection fraction （RVEF） also decreased （P〈0.01）.During the period from 3 to 6 months,the size of the right atrium and right ventricle returned to normal range.Three days after PTSC,the left ventricular end-diastolic diameter （LVEDD）,left ventricular end-diastolic volume （LVEDV）,left ventricular end-systolic volume （LVESV）,left ventricular-systolic volume （LVSV） and left ventricular ejection fraction （LVEF） were significantly increased （P 〈0.05）.At 1 year,the size of the left atrium,left ventricle and left cardiac function returned to normal range （P 〈0.01）.There were no deaths or significant complications during the study.At five year follow-up,all defects were completely closed and remained closed thereafter.Conclusion Transcatheter closure of ASD Ⅱ effectively eliminated the abnormal shunt and,subsequently improved the dimensions of each chamber and cardiac function.
Bibliography:11-2154/R
congenital heart disease; heart septal defects; atrial; interventional
Background The percutaneous transcatheter closure of secundum atrial septal defect （ASD） is increasingly a widespread alternative to surgical closure.The aim of this study was to assess long-term results of percutaneous closure of secundum-type atrial septal defect （ASD Ⅱ）.Methods Between January 2001 and December 2005,61 patients underwent a successful percutaneous closure of ASD Ⅱ; including 25 male and 36 female.All were included in the patient study and were followed up to monitor by electrocardiogram and echocardiography,at intervals of 3 days,3 months,6 months,1 year,2 years,and 5 years after operation.Results Three days after percutaneous transcatheter septal closure （PTSC）,the right atrium diameter,right ventricular end-diastolic left-right diameter and right ventricutar end-diastolic volume （RVEDV） decreased significantly （P 〈0.05）.Right ventricular end-diastolic anteroposterior diameter （RVEDD）,right ventricular end-systolic volume （RVESV） and right ventricular ejection fraction （RVEF） also decreased （P〈0.01）.During the period from 3 to 6 months,the size of the right atrium and right ventricle returned to normal range.Three days after PTSC,the left ventricular end-diastolic diameter （LVEDD）,left ventricular end-diastolic volume （LVEDV）,left ventricular end-systolic volume （LVESV）,left ventricular-systolic volume （LVSV） and left ventricular ejection fraction （LVEF） were significantly increased （P 〈0.05）.At 1 year,the size of the left atrium,left ventricle and left cardiac function returned to normal range （P 〈0.01）.There were no deaths or significant complications during the study.At five year follow-up,all defects were completely closed and remained closed thereafter.Conclusion Transcatheter closure of ASD Ⅱ effectively eliminated the abnormal shunt and,subsequently improved the dimensions of each chamber and cardiac function.
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ISSN:0366-6999
2542-5641
2542-5641
DOI:10.3760/cma.j.issn.0366-6999.2012.01.028