Transcriptional state and function of CD8 + memory T cells is linked to past proliferation

A new genetic ‘recorder’ of long-term cell proliferation revealed substantial heterogeneity in the division history of central memory CD8+ T cells. Importantly, the extent of past proliferation was related to distinct transcriptional features and re-expansion potential, highlighting an unappreciated...

Celý popis

Podrobná bibliografie

Vydáno v:	Nature immunology Ročník 23; číslo 5; s. 658 - 659
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Nature Publishing Group 01.05.2022
Témata:	CD8 antigen Cell cycle Cell growth Cell proliferation Division of labor Genetic engineering Heterogeneity Immunological memory Immunology Infections Lymphocytes Lymphocytes T Memory cells Population Stem cells
ISSN:	1529-2908, 1529-2916, 1529-2916
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!