Quantitative Characterization of Microtubule Ultrastructure Based on Single‐Molecule Localization Microscopy

Single‐molecule localization microscopy (SMLM) enables visualization of cytoskeletal architecture at nanoscale, uncovering ultrastructural details obscured in conventional imaging. In this study, we present a quantitative framework for characterizing microtubule continuity and integrity based on SML...

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Bibliographic Details

Published in:	Cytoskeleton (Hoboken, N.J.)
Main Authors:	Xie, Zhao, Hu, Fen, Chen, Mingxin, Wang, Bo, Li, Jiqiang, Liu, Shuai, Ding, Dan, Lee, Imshik, Yin, Wei, Pan, Leiting
Format:	Journal Article
Language:	English
Published:	United States 30.07.2025
Subjects:	immunofluorescence imaging single‐molecule localization microscopy (SMLM) chemical fixation microtubules computational algorithm super‐resolution imaging
ISSN:	1949-3584, 1949-3592, 1949-3592
Online Access:	Get full text
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