Qa-1b Modulates Resistance to Anti-PD-1 Immune Checkpoint Blockade in Tumors with Defects in Antigen Processing

Immune checkpoint blockade (ICB) has improved cancer care, but ICB is only effective in some patients. The molecular mechanisms that influence ICB therapy response are not completely understood. The non-classical MHC class I molecule HLA-E and its mouse ortholog, Qa-1b, present a limited set of pept...

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Vydané v:	Molecular cancer research Ročník 19; číslo 6; s. 1076
Hlavní autori:	Zhang, Xiao, Sabio, Erich, Krishna, Chirag, Ma, Xiaoxiao, Wang, Jingming, Jiang, Hui, Havel, Jonathan J, Chan, Timothy A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	01.06.2021
ISSN:	1557-3125, 1557-3125
On-line prístup:	Zistit podrobnosti o prístupe
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