Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution. 1. Physiologic concepts

The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of two part series, are summarized the physiologic principles on which the analysis of...

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Vydáno v:Intensive care medicine Ročník 20; číslo 4; s. 291
Hlavní autoři: Marshall, B E, Marshall, C, Frasch, F, Hanson, C W
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.04.1994
Témata:
Humans
Hypoxia - physiopathology
Pulmonary Artery - physiology
Pulmonary Circulation - physiology
Pulmonary Gas Exchange - physiology
Pulmonary Veins - physiology
Vasoconstriction - physiology
Ventilation-Perfusion Ratio - physiology
ISSN:0342-4642
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Shrnutí:The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of two part series, are summarized the physiologic principles on which the analysis of ventilation/perfusion ratios and of pressure-flow relationships are based. A new combined analysis is introduced that permits the important contributions of hypoxic pulmonary vasoconstriction to overall gas exchange to be demonstrated in the circumstances of clinical complexity.
Bibliografie:ObjectType-Article-1
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ISSN:0342-4642
DOI:10.1007/BF01708968