Pegcetacoplan compared with supportive care for 26 weeks for participants with paroxysmal nocturnal hemoglobinuria: a plain language summary

In the PRINCE study, adults with paroxysmal nocturnal hemoglobinuria (PNH) who had not recently taken a C5 complement inhibitor medicine received pegcetacoplan or supportive care. Pegcetacoplan reduced hemolysis better than supportive care and was well tolerated.

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Bibliographic Details
Published in:	Future Rare Diseases Vol. 4; no. 1
Main Authors:	Ming Wong, Raymond Siu, Navarro-Cabrera, Juan Ramon, Comia, Narcisa Sonia, Goh, Yeow Tee, Idrobo, Henry, Kongkabpan, Daolada, Gómez-Almaguer, David, Al-Adhami, Mohammed, Ajayi, Temitayo, Alvarenga, Paulo, Savage, Jessica, Deschatelets, Pascal, Francois, Cedric, Grossi, Federico, Dumagay, Teresita
Format:	Journal Article
Language:	English
Published:	Future Medicine Ltd 31.12.2024
Subjects:	anemia lay summary paroxysmal nocturnal hemoglobinuria pegcetacoplan plain language summary
ISSN:	2399-5262, 2399-5270, 2399-5270
Online Access:	Get full text
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Description
Summary:	In the PRINCE study, adults with paroxysmal nocturnal hemoglobinuria (PNH) who had not recently taken a C5 complement inhibitor medicine received pegcetacoplan or supportive care. Pegcetacoplan reduced hemolysis better than supportive care and was well tolerated.
ISSN:	2399-5262 2399-5270 2399-5270
DOI:	10.2217/frd-2023-0006