Analysis of Intervertebral Fixation Systems in a Rat Caudal Model of Spinal Fusion
Study Design: Original research article. Objectives: This study compared the stiffness of established and novel fixation systems when applied to the caudal segment in Sprague-Dawley rats in an ex vivo trial. Study of Literature Review: Segmental hypermobility necessitates the application of model-sp...
Uloženo v:
| Vydáno v: | Journal of Korean Society of Spine Surgery Ročník 31; číslo 3; s. 96 - 107 |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
대한척추외과학회
01.09.2024
|
| Témata: | |
| ISSN: | 2093-4378, 2093-4386 |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Shrnutí: | Study Design: Original research article.
Objectives: This study compared the stiffness of established and novel fixation systems when applied to the caudal segment in Sprague-Dawley rats in an ex vivo trial.
Study of Literature Review: Segmental hypermobility necessitates the application of model-specific intervertebral fixation.
Materials and Methods: Six fixation systems (external k-wires, internal k-wire, titanium plate, polymer plate, polymer plate with spacer attachment [polymer T], and polymer plate with spacer attachment and ventral hook [polymer I]) were acquired or fabricated.
These were compared to three control groups. Ninety-nine segments from coccygeal (Co) levels Co3 to Co8 were randomly allocated to the nine groups. Surgical implantation was timed, and segments were prepared and evaluated via micro-computed tomography imaging for inclusion. Four-point quasistatic bend testing was used to derive sample stiffness in ventral and lateral flexion.
Results: In the ventral flexion position, external K-wires and polymer I fixation groups (mean ± standard deviation) displayed significantly greater bending stiffness of 9.11±7.55 N/mm2 and 9.66 ± 6.15 N/mm2 when compared to the control with no surgery (p=0.013 and 0.005), respectively. In the lateral flexion position, the polymer I group had significantly greater bending stiffness (3.32±1.57 N/mm2) than the nosurgery control (p=0.023).
Conclusions: The novel polymer I fixation device showed superior segmental stiffness in ventral and lateral flexion compared to the control that did not undergo surgery, and other established external stabilisation devices. Further research should assess viability and methodology of internal fixation systems for in vivo implantation. KCI Citation Count: 0 |
|---|---|
| ISSN: | 2093-4378 2093-4386 |
| DOI: | 10.4184/jkss.2024.31.3.96 |