DNA-Based Storage: Trends and Methods

We provide an overview of current approaches to DNA-based storage system design and of accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random access DNA storage channels. The analytic contribution o...

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Bibliographic Details
Published in:IEEE transactions on molecular, biological, and multi-scale communications Vol. 1; no. 3; pp. 230 - 248
Main Authors: Hossein Tabatabaei Yazdi, S. M., Han Mao Kiah, Garcia-Ruiz, Eva, Jian Ma, Huimin Zhao, Milenkovic, Olgica
Format: Journal Article
Language:English
Published: IEEE 01.09.2015
Subjects:
Chemicals
Couplings
DNA
Encoding
Media
Sequential analysis
DNA synthesis and sequencing
DNA-based storage
Constrained and error-control coding
ISSN:2372-2061, 2372-2061
Online Access:Get full text
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Summary:We provide an overview of current approaches to DNA-based storage system design and of accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random access DNA storage channels. The analytic contribution of our work is the construction and design of sequences over discrete alphabets that avoid pre-specified address patterns, have balanced base content, and exhibit other relevant substring constraints. These schemes adapt the stored signals to the DNA medium and thereby reduce the inherent error-rate of the system.
ISSN:2372-2061
2372-2061
DOI:10.1109/TMBMC.2016.2537305