Partial bilateral mesencephalic lesions affect D1 but not D2 binding in both the striatum and cortex

The substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA) are the two major mesencephalic dopaminergic systems. Mesencephalic dopamine denervation is followed by long-term modifications in striatum and cortex that preserve dopamine functions. Here, we have studied the impact of i...

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Bibliographic Details
Published in:	Neurochemistry international Vol. 45; no. 7; pp. 995 - 1004
Main Authors:	Pioli, Elsa, Sohr, Reinhard, Meissner, Wassilios, Barthe, Nicole, Gross, Christian E., Bezard, Erwan, Bioulac, Bernard H.
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier 01.12.2004
Subjects:	Animals Biological and medical sciences Cerebral Cortex - metabolism Corpus Striatum - metabolism Fundamental and applied biological sciences. Psychology Mesencephalon - metabolism Protein Binding - physiology Rats Rats, Wistar Receptors, Dopamine D1 - metabolism Receptors, Dopamine D2 - metabolism Vertebrates: nervous system and sense organs Dopamine Locus niger Central nervous system Neurotransmitter Midbrain Basal ganglion Corpus striatum Lesion Substantia nigra pars compacta Catecholamine Ventral tegmental area Encephalon
ISSN:	0197-0186
Online Access:	Get full text
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