KYNURENINE PATHWAY INHIBITORS COMBINED WITH NAD+ PRECURSORS INCREASES LONGEVITY GENE EXPRESSION IN DROSOPHILA

Abstract With rates of aging-related functional decline rising, the need for novel intervention strategies to extend lifespan has increased. In humans, the kynurenine pathway (KP) metabolizes tryptophan and produces nicotinamide adenine dinucleotide (NAD+). KP is correlated negatively with longevity...

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Bibliographic Details

Published in:	Innovation in aging Vol. 7; no. Supplement_1; p. 1073
Main Authors:	Said, Adam, Huang, Qiao, Wu, Yuqiong, Walston, Jeremy, Westbrook, Reyhan, Abadir, Peter M
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 21.12.2023
Subjects:	Insects
ISSN:	2399-5300, 2399-5300
Online Access:	Get full text
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