KYNURENINE PATHWAY INHIBITORS COMBINED WITH NAD+ PRECURSORS INCREASES LONGEVITY GENE EXPRESSION IN DROSOPHILA

Abstract With rates of aging-related functional decline rising, the need for novel intervention strategies to extend lifespan has increased. In humans, the kynurenine pathway (KP) metabolizes tryptophan and produces nicotinamide adenine dinucleotide (NAD+). KP is correlated negatively with longevity...

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Vydané v:	Innovation in aging Ročník 7; číslo Supplement_1; s. 1073
Hlavní autori:	Said, Adam, Huang, Qiao, Wu, Yuqiong, Walston, Jeremy, Westbrook, Reyhan, Abadir, Peter M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	US Oxford University Press 21.12.2023
Predmet:	Insects
ISSN:	2399-5300, 2399-5300
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