Preclinical evaluation of antigen-specific B-cell depletion for phospholipase A2 receptor membranous nephropathy with chimeric autoantibody receptor T cells

Phospholipase A2 receptor (PLA2R)-associated membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults, driven by autoantibodies that target PLA2R on kidney podocytes. Antibody-based therapy with rituximab induces broad B-cell depletion but is associated with risks of serious in...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Kidney international
Hlavní autori:	Altun, Burcin, Zhao, Gexin, Wang, Baomei, Mao, Xuming, Manfredo-Vieira, Silvio, Willis, Elinor, Radaelli, Enrico, Goodman, Emma E, Boesteanu, Alina C, Gill, Saar I, Patel, Darshil R, Wong, Steven, Cottman-Thomas, Ebony, Hogan, Jonathan J, Payne, Aimee S
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 31.10.2025
Predmet:	nephrology kidney chimeric antigen receptor autoimmunity cell therapy
ISSN:	1523-1755, 1523-1755
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!