Cracking Controls ATP Hydrolysis in the Catalytic Unit of a P-type ATPase

[Display omitted] •The isolated AfCopA-NP catalytic unit conserves its optimal working temperature and apparent affinity for ATP.•Small additions of urea increase ATPase activity.•A characterization of the native conformational ensemble was performed by a combination of local frustration and AlphaFo...

Celý popis

Podrobná bibliografia

Vydané v:	Journal of molecular biology Ročník 438; číslo 2; s. 169551
Hlavní autori:	Placenti, M. Agueda, Martinez-Gache, Santiago A., González-Lebrero, Rodolfo M., Wolynes, Peter G., González Flecha, F. Luis, Roman, Ernesto A.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Netherlands Elsevier Ltd 20.11.2025
Predmet:	ATPase activity catalytic unit local frustration local unfolding PIB-ATPases local frustration PIB-ATPases catalytic unit ATPase activity local unfolding P(IB)-ATPases
ISSN:	0022-2836, 1089-8638, 1089-8638
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!