Back Cover: Ligand Dilution Analysis Facilitates Aptamer Binding Characterization at the Single‐Molecule Level (Angew. Chem. Int. Ed. 10/2023)

A membrane‐receptor‐analysis method termed ligand dilution analysis, which combines the concepts of single‐molecule localization and random sampling, is reported by Yifan Lyu, Jianhui Jiang, Weihong Tan et al. in their Research Article (e202215387). Aptamer binding characterization, including recept...

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Vydáno v:Angewandte Chemie International Edition Ročník 62; číslo 10
Hlavní autoři: Du, Yulin, Lyu, Yifan, Li, Shiquan, Ding, Ding, Chen, Jianghuai, Yang, Cai, Sun, Yang, Qu, Fengli, Xiao, Zeyu, Jiang, Jianhui, Tan, Weihong
Médium: Journal Article
Jazyk:angličtina
Vydáno: 01.03.2023
Témata:
Aptamers
Binding Site
Dilution
Fluorescent Probes
Motion Analysis
ISSN:1433-7851, 1521-3773
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Shrnutí:A membrane‐receptor‐analysis method termed ligand dilution analysis, which combines the concepts of single‐molecule localization and random sampling, is reported by Yifan Lyu, Jianhui Jiang, Weihong Tan et al. in their Research Article (e202215387). Aptamer binding characterization, including receptor density calculation, single‐molecule colocalization, binding site determination, motion and fluctuation analysis, was performed with minimal probe and instrument requirements.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.202301456