Back Cover: Ligand Dilution Analysis Facilitates Aptamer Binding Characterization at the Single‐Molecule Level (Angew. Chem. Int. Ed. 10/2023)

A membrane‐receptor‐analysis method termed ligand dilution analysis, which combines the concepts of single‐molecule localization and random sampling, is reported by Yifan Lyu, Jianhui Jiang, Weihong Tan et al. in their Research Article (e202215387). Aptamer binding characterization, including recept...

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 62; no. 10
Main Authors:	Du, Yulin, Lyu, Yifan, Li, Shiquan, Ding, Ding, Chen, Jianghuai, Yang, Cai, Sun, Yang, Qu, Fengli, Xiao, Zeyu, Jiang, Jianhui, Tan, Weihong
Format:	Journal Article
Language:	English
Published:	01.03.2023
Subjects:	Aptamers Binding Site Dilution Fluorescent Probes Motion Analysis
ISSN:	1433-7851, 1521-3773
Online Access:	Get full text
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Summary:	A membrane‐receptor‐analysis method termed ligand dilution analysis, which combines the concepts of single‐molecule localization and random sampling, is reported by Yifan Lyu, Jianhui Jiang, Weihong Tan et al. in their Research Article (e202215387). Aptamer binding characterization, including receptor density calculation, single‐molecule colocalization, binding site determination, motion and fluctuation analysis, was performed with minimal probe and instrument requirements.
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.202301456