Back Cover: Ligand Dilution Analysis Facilitates Aptamer Binding Characterization at the Single‐Molecule Level (Angew. Chem. Int. Ed. 10/2023)

A membrane‐receptor‐analysis method termed ligand dilution analysis, which combines the concepts of single‐molecule localization and random sampling, is reported by Yifan Lyu, Jianhui Jiang, Weihong Tan et al. in their Research Article (e202215387). Aptamer binding characterization, including recept...

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Veröffentlicht in:Angewandte Chemie International Edition Jg. 62; H. 10
Hauptverfasser: Du, Yulin, Lyu, Yifan, Li, Shiquan, Ding, Ding, Chen, Jianghuai, Yang, Cai, Sun, Yang, Qu, Fengli, Xiao, Zeyu, Jiang, Jianhui, Tan, Weihong
Format: Journal Article
Sprache:Englisch
Veröffentlicht: 01.03.2023
Schlagworte:
Aptamers
Binding Site
Dilution
Fluorescent Probes
Motion Analysis
ISSN:1433-7851, 1521-3773
Online-Zugang:Volltext
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Zusammenfassung:A membrane‐receptor‐analysis method termed ligand dilution analysis, which combines the concepts of single‐molecule localization and random sampling, is reported by Yifan Lyu, Jianhui Jiang, Weihong Tan et al. in their Research Article (e202215387). Aptamer binding characterization, including receptor density calculation, single‐molecule colocalization, binding site determination, motion and fluctuation analysis, was performed with minimal probe and instrument requirements.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.202301456