DYNAMICS OF SERUM IRON LEVELS IN POTENTIAL DONORS DURING PROTECTIVE INTENSIVE THERAPY
Background. At present, the dynamics of serum iron in organ and tissue donors with traumatic and non-traumatic brain injuries have not been reliably established. The aim of this study was to investigate the dynamics of serum iron levels in potential organ and tissue donors. Material and methods. The...
Uložené v:
| Vydané v: | Zhurnal Grodnenskogo gosudarstvennogo medit͡s︡inskogo universiteta Ročník 23; číslo 4; s. 347 - 352 |
|---|---|
| Hlavní autori: | , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
01.09.2025
|
| ISSN: | 2221-8785, 2413-0109 |
| On-line prístup: | Získať plný text |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | Background. At present, the dynamics of serum iron in organ and tissue donors with traumatic and non-traumatic brain injuries have not been reliably established. The aim of this study was to investigate the dynamics of serum iron levels in potential organ and tissue donors. Material and methods. The prospective study included 266 potential donors with brain death. The donors' serum iron levels were determined at three stages: stage 1 – after the 1st examination by the council to confirm brain death; stage 2 – 18-24 hours after the 1st examination by the council; stage 3 – after the 2nd examination and confirmation of brain death. Results. The iron level at stage 1 was 3.32 (2.26; 5.4) μmol / l (the iron level was within the reference values in 16 (6%) donors). At stage 2, the serum iron level was 3.23 (2.38; 5.32) μmol/l (p=0.96). At stage 3, the iron level statistically significantly increased to 3.59 (2.56; 6.02) μmol/l (vs stage 2, p=0.015). Donors with traumatic brain injury had lower iron levels at stage 1 compared to those with non-traumatic injuries: 2.67 (1.65; 4.24) μmol/l and 3.4 (2.49; 5.61) μmol/l, respectively, p=0.026. A statistically significant inverse correlation was found between the volume of intracranial hematoma and the serum iron level at stage 1 of the study: R=-0.29, p=0.05. Conclusions. In brain-dead potential donors, serum iron levels decrease significantly during protective intensive care. |
|---|---|
| AbstractList | Background. At present, the dynamics of serum iron in organ and tissue donors with traumatic and non-traumatic brain injuries have not been reliably established. The aim of this study was to investigate the dynamics of serum iron levels in potential organ and tissue donors. Material and methods. The prospective study included 266 potential donors with brain death. The donors' serum iron levels were determined at three stages: stage 1 – after the 1st examination by the council to confirm brain death; stage 2 – 18-24 hours after the 1st examination by the council; stage 3 – after the 2nd examination and confirmation of brain death. Results. The iron level at stage 1 was 3.32 (2.26; 5.4) μmol / l (the iron level was within the reference values in 16 (6%) donors). At stage 2, the serum iron level was 3.23 (2.38; 5.32) μmol/l (p=0.96). At stage 3, the iron level statistically significantly increased to 3.59 (2.56; 6.02) μmol/l (vs stage 2, p=0.015). Donors with traumatic brain injury had lower iron levels at stage 1 compared to those with non-traumatic injuries: 2.67 (1.65; 4.24) μmol/l and 3.4 (2.49; 5.61) μmol/l, respectively, p=0.026. A statistically significant inverse correlation was found between the volume of intracranial hematoma and the serum iron level at stage 1 of the study: R=-0.29, p=0.05. Conclusions. In brain-dead potential donors, serum iron levels decrease significantly during protective intensive care. |
| Author | Kupreyeva, I. A. Marochkov, A. V. Lipnitski, A. L. |
| Author_xml | – sequence: 1 givenname: A. L. orcidid: 0000-0002-2556-4801 surname: Lipnitski fullname: Lipnitski, A. L. – sequence: 2 givenname: A. V. orcidid: 0000-0001-5092-8315 surname: Marochkov fullname: Marochkov, A. V. – sequence: 3 givenname: I. A. orcidid: 0000-0002-5745-1203 surname: Kupreyeva fullname: Kupreyeva, I. A. |
| BookMark | eNo1kElrwzAQhUVJoWma_6BDr2o1WmwJejGOkhgcO3gJ5CS8yNDSJsU-9d9X7nKZefAew7zvHi0u14tD6BHoE5NMq2fGGBAVKkkYZX5wIggXIeGS3aAlE8AJBaoXXv8n79B6mt4opaBYEAIsUb05Z9EhiUucb3FpivqAkyLPcGpOJi1xkuFjXpmsSqIUb_IsL0q8qYsk2-Fj4Y24Sk7Gp3yknFW1N0V0PD-g26F5n9z6b69QvTVVvCdpvkviKCUd0JD5v0EI3vFWMghacH2vqXYauNO0D0Fq2XIZOtUrPSjngsA1TDYDdBoCLVrFV-jl9243XqdpdIP9HF8_mvHLArU_lOzc3c7d7UzJMm6F9ZSsp8S_AbQAVL4 |
| ContentType | Journal Article |
| CorporateAuthor | Mogilev Regional Clinical Hospital, Mogilev, Belarus Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Belarus |
| CorporateAuthor_xml | – name: Mogilev Regional Clinical Hospital, Mogilev, Belarus – name: Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Belarus |
| DBID | AAYXX CITATION |
| DOI | 10.25298/2221-8785-2025-23-4-347-352 |
| DatabaseName | CrossRef |
| DatabaseTitle | CrossRef |
| DatabaseTitleList | CrossRef |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2413-0109 |
| EndPage | 352 |
| ExternalDocumentID | 10_25298_2221_8785_2025_23_4_347_352 |
| GroupedDBID | AAYXX ALMA_UNASSIGNED_HOLDINGS CITATION GROUPED_DOAJ VCL VIT |
| ID | FETCH-LOGICAL-c1072-201443c3b5216b1edd909e913e90d71595b357e8d89f8ee66ea25af1c91694b83 |
| ISSN | 2221-8785 |
| IngestDate | Sat Nov 29 07:35:40 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c1072-201443c3b5216b1edd909e913e90d71595b357e8d89f8ee66ea25af1c91694b83 |
| ORCID | 0000-0002-5745-1203 0000-0002-2556-4801 0000-0001-5092-8315 |
| OpenAccessLink | http://journal-grsmu.by/index.php/ojs/article/download/3318/2931 |
| PageCount | 6 |
| ParticipantIDs | crossref_primary_10_25298_2221_8785_2025_23_4_347_352 |
| PublicationCentury | 2000 |
| PublicationDate | 2025-09-00 |
| PublicationDateYYYYMMDD | 2025-09-01 |
| PublicationDate_xml | – month: 09 year: 2025 text: 2025-09-00 |
| PublicationDecade | 2020 |
| PublicationTitle | Zhurnal Grodnenskogo gosudarstvennogo medit͡s︡inskogo universiteta |
| PublicationYear | 2025 |
| SSID | ssj0001826711 |
| Score | 2.3021278 |
| Snippet | Background. At present, the dynamics of serum iron in organ and tissue donors with traumatic and non-traumatic brain injuries have not been reliably... |
| SourceID | crossref |
| SourceType | Index Database |
| StartPage | 347 |
| Title | DYNAMICS OF SERUM IRON LEVELS IN POTENTIAL DONORS DURING PROTECTIVE INTENSIVE THERAPY |
| Volume | 23 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 2413-0109 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001826711 issn: 2221-8785 databaseCode: DOA dateStart: 20030101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELfKQIgXBALE2EB-WJ-ilMbOlx9Dm7KIklRtWg1eonx4oxpKqjWt9qfy53COkzTbAxpIvETWObmccj-d75w7H0Jnph1TlsWGmoLzoOqpZqpxrHEV1oKYWDFLs6rqfTW1fN--uGCzXu9XUwuz_2nluX17yzb_VdVAA2WL0tm_UHfLFAgwBqXDFdQO1wcpfvzNd0RnQpHPs3Dny6-KNw98ZSq6bYp6YWUWhK4fes5UGQd-MF8o46VIiQBlwMQo9FaiDT3cshCj8NydO7M7Puz3H9KH_Qy2N4co-Lq4KpSrYrvLIEguwXjmgiB-2pf90bjvaNu-O-l_smG0ru_eNekgvGyXhel6A-albqPtDJTp4LBbLvp6XRf7embVznzZbQCKfF95wN4AJru7GMRo07RqYwduigaWWbbvGXBJ00XnCW3IutZaVifXqNQ7ppfKkzvrVZzKc3HvLxDEIExUPbSvUythCFV1FRio9WN3z-W-t162WYwQP1X8IsEtEtwiwS0iNNIj4BYBt0foMbEMxjrBfrX7B1GdVTWHbiV5is4aAT_-QbyO_9RxhMIX6HkdwWBHIu8l6vH8FVo2qMPBBFeowwJ1WKIOez5uUYcl6rBEHT6gDreowzXqXqPlxA1H52rdsUNNtaFFQFqIz2lKE3AKzUTjWcaGjDONcjbMLPCcjYQaFrczm13anJsmj4kRX2opBClMT2z6Bh3lRc7fIqwlmW7aZiLIemrROOOxyYkOwaDJCOHHyGi-Q7SRB7NED1HIu3987gQ9O-D2FB2VNzv-Hj1J9-V6e_Oh0u5vW0xzSg |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=DYNAMICS+OF+SERUM+IRON+LEVELS+IN+POTENTIAL+DONORS+DURING+PROTECTIVE+INTENSIVE+THERAPY&rft.jtitle=Zhurnal+Grodnenskogo+gosudarstvennogo+medit%CD%A1s%EF%B8%A1inskogo+universiteta&rft.au=Lipnitski%2C+A.+L.&rft.au=Marochkov%2C+A.+V.&rft.au=Kupreyeva%2C+I.+A.&rft.date=2025-09-01&rft.issn=2221-8785&rft.eissn=2413-0109&rft.volume=23&rft.issue=4&rft.spage=347&rft.epage=352&rft_id=info:doi/10.25298%2F2221-8785-2025-23-4-347-352&rft.externalDBID=n%2Fa&rft.externalDocID=10_25298_2221_8785_2025_23_4_347_352 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2221-8785&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2221-8785&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2221-8785&client=summon |