The PIN1-p38-CtIP signaling axis protects stalled replication forks from deleterious degradation

Human CtIP plays a critical role in homologous recombination (HR) by promoting the resection of DNA double-strand breaks. Moreover, CtIP maintains genome stability through protecting stalled replication forks from nucleolytic degradation. However, the upstream signaling mechanisms governing the mole...

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Bibliographic Details

Published in:	bioRxiv
Main Authors:	Vivalda, Francesca, Gatti, Marco, Manfredi, Letizia, Dogan, Hülya, Porro, Antonio, Collotta, Giulio, Ceppi, Ilaria, von Aesch, Christine, van Ackeren, Vanessa, Wild, Sebastian, Steger, Martin, Canovas, Begoña, Cubillos-Rojas, Monica, Riera, Antoni, Cejka, Petr, Nebreda, Angel R., Dibitetto, Diego, Rottenberg, Sven, Sartori, Alessandro A.
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Laboratory 26.06.2024
Edition:	1.1
Subjects:	Molecular Biology
ISSN:	2692-8205
Online Access:	Get full text
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