Marine Drug Discovery through Computer-Aided Approaches

Computer-Aided Ligand- and Structure-based methodologies are an evolving field in the discovery of Marine Drugs. Computational approaches, chemistry simulation methods using bioinformatics and chemoinformatics tools and databases can be successfully used in the discovery, design and development of n...

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Format: E-Book
Sprache:Englisch
Veröffentlicht: MDPI - Multidisciplinary Digital Publishing Institute 2024
Schlagworte:
activity relationship (QSAR)
assisted structure elucidation (CASE) drug discovery
bioinformatics
biological space
blue biotechnology
chemical space
chemoinformatics
Computer science
computer&ndash
computer-aided drug design (CADD)
Computing and Information Technology
dereplication
drug repurposing
machine learning techniques
Marine Natural Products databases
molecular docking
quantitative structure&ndash
ISBN:3036599126, 3036599118, 9783036599120, 9783036599113
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:Computer-Aided Ligand- and Structure-based methodologies are an evolving field in the discovery of Marine Drugs. Computational approaches, chemistry simulation methods using bioinformatics and chemoinformatics tools and databases can be successfully used in the discovery, design and development of new chemical agents for therapeutic purposes by assisting in the structure elucidation of secondary metabolites, repurposing known Marine Natural Products (MNPs) for innovative therapeutic targets, identifying novel hits or leads against selected therapeutic targets and revealing mechanisms of action and supporting medicinal chemistry lead optimization programs. This Special Issue of Marine Drugs entitled “Marine Drug Discovery through Computer-Aided Approaches” aims to provide a comprehensive overview of the great variety of existing and advanced Computer-Aided Approaches for the discovery and identification of molecular agents with added value and health-promoting properties for the development of biotechnological and medical applications.
ISBN:3036599126
3036599118
9783036599120
9783036599113
DOI:10.3390/books978-3-0365-9912-0