Treatments for dry age-related macular degeneration: therapeutic avenues, clinical trials and future directions

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the developed world. The identification of the central role of vascular endothelial growth factor (VEGF) in the pathogenesis of neovascular AMD and the introduction of anti-VEGF agents as gold-standard treatment...

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Bibliographic Details
Published in:	British journal of ophthalmology Vol. 106; no. 3; pp. 297 - 304
Main Authors:	Cabral de Guimaraes, Thales Antonio, Daich Varela, Malena, Georgiou, Michalis, Michaelides, Michel
Format:	Journal Article
Language:	English
Published:	BMA House, Tavistock Square, London, WC1H 9JR BMJ Publishing Group Ltd 01.03.2022 BMJ Publishing Group LTD BMJ Publishing Group
Subjects:	angiogenesis Angiogenesis Inhibitors - therapeutic use Antioxidants Clinical trials degeneration Fatty acids Genes genetics Geographic Atrophy - therapy GLP-1 receptor agonists Health risk assessment Humans Lasers macula Macular degeneration Older people Oxidative stress Pathogenesis Pharmaceuticals R&D Research & development retina Review Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics Visual Acuity Wet Macular Degeneration - drug therapy United Kingdom > UK Australia United States > US genetics retina angiogenesis degeneration macula
ISSN:	0007-1161, 1468-2079, 1468-2079
Online Access:	Get full text
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