Basic and advanced imaging of a case of Balò's concentric sclerosis

(C) Perfusion MRI analysis, based on four regions of interest depicted in D (A, pink, B, white, C, blue, D, red) suggests that the central layers of the ring are more perfused compared to the peripheral ones. n The spectroscopic image (figure 2B) of the lesion documented increased choline peak and d...

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Veröffentlicht in:	BMJ case reports Jg. 2013; S. bcr2012008413
Hauptverfasser:	Ripellino, Paolo, Stecco, Alessandro, Leone, Maurizio A, Cantello, Roberto
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England BMJ Publishing Group Ltd 25.01.2013 BMJ Publishing Group LTD BMJ Publishing Group
Schriftenreihe:	Images in
Schlagworte:	51-70 years Biopsy Diffuse Cerebral Sclerosis of Schilder - diagnosis Diffuse Cerebral Sclerosis of Schilder - drug therapy Diffusion Magnetic Resonance Imaging Europe (West) Female Humans Images In Magnetic Resonance Angiography Middle Aged Spectrum Analysis White
ISSN:	1757-790X, 1757-790X
Online-Zugang:	Volltext
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Zusammenfassung:	(C) Perfusion MRI analysis, based on four regions of interest depicted in D (A, pink, B, white, C, blue, D, red) suggests that the central layers of the ring are more perfused compared to the peripheral ones. n The spectroscopic image (figure 2B) of the lesion documented increased choline peak and decreased N-acetyl aspartate peak, but normal peaks in the normal appearing white matter near the lesion.1 The perfusion analysis (figure 2C), based on four different regions of interest (figure 2D), suggested a decreasing gradient of perfusion from the centre to the periphery of the lesion, supporting the hypothesis that the centre of the ring corresponds anatomically to a deep venous vessel.3 Authors are not aware of previous report of perfusion studies in Balò's sclerosis. n Cerebrospinal fluid analysis detected oligoclonal bands, without anti-aquaporin-4 antibodies. The right paresis fully recovered after 2 weeks and has not relapsed after 11 months. n The 8 months follow-up MRI showed a reduction in the lesion volume and absence of new demyelinating lesions (figure 3A,B). (A) Axial fluid attenuated inversion recovery sequence and (B) sagittal T2-sequence evidence the reduction in the lesion volume compared to figure 1.
Bibliographie:	Images in... ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Report-3 ObjectType-Case Study-4 ObjectType-Case Study-2 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1757-790X 1757-790X
DOI:	10.1136/bcr-2012-008413