The prevalence of lymphogranuloma venereum infection in men who have sex with men: results of a multicentre case finding study

Objective: To determine the prevalence of lymphogranuloma venereum (LGV) and non-LGV associated serovars of urethral and rectal Chlamydia trachomatis (CT) infection in men who have sex with men (MSM). Design: Multicentre cross-sectional survey. Setting: Four genitourinary medicine clinics in the Uni...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sexually transmitted infections Ročník 85; číslo 3; s. 173 - 175
Hlavní autoři: Ward, H, Alexander, S, Carder, C, Dean, G, French, P, Ivens, D, Ling, C, Paul, J, Tong, W, White, J, Ison, C A
Médium: Journal Article
Jazyk:angličtina
Vydáno: London BMJ Publishing Group 01.06.2009
BMJ Publishing Group LTD
Témata:
Ambulatory Care Facilities
Bacterial diseases
Bacterial diseases of the genital system
Biological and medical sciences
Chlamydia Infections - diagnosis
Chlamydia Infections - epidemiology
Chlamydia trachomatis
Chlamydia trachomatis - isolation & purification
Clinical
Clinics
Cross-Sectional Studies
Data collection
Epidemics
Epidemiology. Vaccinations
FDA approval
General aspects
HIV
Homosexuality, Male
Human bacterial diseases
Human immunodeficiency virus
Human infectious diseases. Experimental studies and models
Humans
Infections
Infectious diseases
Laboratories
Lymphogranuloma Venereum - diagnosis
Lymphogranuloma Venereum - epidemiology
Male
Mass Screening
Medical sciences
Mens health
Patients
Prevalence
Rectal Diseases - epidemiology
Risk Factors
Toys
United Kingdom - epidemiology
Urethral Diseases - epidemiology
Urine
United Kingdom > UK
Australia
Europe
Infection
Case study
Human
Homosexuality
Sexually transmitted disease
Prevalence
Bacteriosis
Lymphogranuloma venereum
Male
Chlamydiosis
Epidemiology
ISSN:1368-4973, 1472-3263, 1472-3263
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Objective: To determine the prevalence of lymphogranuloma venereum (LGV) and non-LGV associated serovars of urethral and rectal Chlamydia trachomatis (CT) infection in men who have sex with men (MSM). Design: Multicentre cross-sectional survey. Setting: Four genitourinary medicine clinics in the United Kingdom from 2006–7. Subjects: 4825 urethral and 6778 rectal samples from consecutive MSM attending for sexual health screening. Methods: Urethral swabs or urine and rectal swabs were tested for CT using standard nucleic acid amplification tests. Chlamydia-positive specimens were sent to the reference laboratory for serovar determination. Main outcome: Positivity for both LGV and non-LGV associated CT serovars; proportion of cases that were symptomatic. Results: The positivity (with 95% confidence intervals) in rectal samples was 6.06% (5.51% to 6.66%) for non-LGV CT and 0.90% (0.69% to 1.16%) for LGV; for urethral samples 3.21% (2.74% to 3.76%) for non-LGV CT and 0.04% (0.01% to 0.16%) for LGV. The majority of LGV was symptomatic (95% of rectal, one of two urethral cases); non-LGV chlamydia was mostly symptomatic in the urethra (68%) but not in the rectum (16%). Conclusions: Chlamydial infections are common in MSM attending for sexual health screening, and the majority are non-LGV associated serovars. We did not identify a large reservoir of asymptomatic LGV in the rectum or urethra. Testing for chlamydia from the rectum and urethra should be included for MSM requesting a sexual health screen, but serovar-typing is not indicated in the absence of symptoms. We have yet to identify the source of most cases of LGV in the UK.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
See Editorial, p 157
ISSN:1368-4973
1472-3263
1472-3263
DOI:10.1136/sti.2008.035311