Bronchoscopy with and without needle-based confocal laser endomicroscopy for peripheral lung nodule diagnosis: protocol for a multicentre randomised controlled trial (CLEVER trial)

IntroductionDespite many technological advances, the diagnostic yield of bronchoscopic peripheral lung nodule analysis remains limited due to frequent mispositioning. Needle-based confocal laser endomicroscopy (nCLE) enables real-time microscopic feedback on needle positioning, potentially improving...

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Veröffentlicht in:	BMJ open Jg. 14; H. 7; S. e081148
Hauptverfasser:	van Heumen, Saskia, Kramer, Tess, Korevaar, Daniël A, Gompelmann, Daniela, Bal, Christina, Hetzel, Juergen, Jahn, Kathleen, Poletti, Venerino, Ravaglia, Claudia, Sadoughi, Ali, Stratakos, Grigoris, Bakiri, Katerina, Koukaki, Evangelia, Anagnostopoulos, Nektarios, Votruba, Jiří, Šestáková, Zuzana, Heuvelmans, Marjolein A, Daniels, Johannes M.A., de Bruin, Daniel M, Bonta, Peter I, Annema, Jouke T
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England British Medical Journal Publishing Group 04.07.2024 BMJ Publishing Group LTD BMJ Publishing Group
Schriftenreihe:	Protocol
Schlagworte:	Biopsy Bronchoscopy Bronchoscopy - methods Cancer therapies Clinical Trial Cytopathology Diagnostic Imaging Feedback Humans Informed consent Lasers Lung - diagnostic imaging Lung - pathology Lung cancer Lung Neoplasms - diagnosis Lung Neoplasms - diagnostic imaging Lung Neoplasms - pathology Medical diagnosis Medical screening Microscopy, Confocal - methods Multicenter Studies as Topic Needles Patients Randomized Controlled Trials as Topic Respiratory Medicine Respiratory tract tumours Solitary Pulmonary Nodule - diagnosis Solitary Pulmonary Nodule - diagnostic imaging Solitary Pulmonary Nodule - pathology Success Ultrasonic imaging Diagnostic Imaging Respiratory tract tumours Cytopathology Clinical Trial Biopsy
ISSN:	2044-6055, 2044-6055
Online-Zugang:	Volltext
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