Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis

ObjectiveBiological insights into the stepwise development and progression of colorectal cancer (CRC) are imperative to develop tailored approaches for early detection and optimal clinical management of this disease. Here, we aimed to dissect the transcriptional and immunologic alterations that acco...

Full description

Saved in:

Bibliographic Details
Published in:	Gut Vol. 72; no. 7; pp. 1326 - 1339
Main Authors:	Roelands, Jessica, van der Ploeg, Manon, Ijsselsteijn, Marieke E, Dang, Hao, Boonstra, Jurjen J, Hardwick, James C H, Hawinkels, Lukas J A C, Morreau, Hans, de Miranda, Noel F C C
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group Ltd and British Society of Gastroenterology 01.07.2023 BMJ Publishing Group LTD BMJ Publishing Group
Series:	Original research
Subjects:	Biomarkers Cancer Cell Transformation, Neoplastic - genetics Colon Colorectal cancer Colorectal carcinoma colorectal neogenesis Colorectal Neoplasms - pathology Cytometry Dysplasia Endoscopy Epithelium Gene expression Gene Expression Profiling Genetic transformation Genomics Histocompatibility antigen HLA Humans immunogenetics Inflammation Macrophages Metastases Myeloid cells Patients Transcriptome Transcriptomics Tumorigenesis Tumors colorectal neogenesis immunogenetics gene expression
ISSN:	0017-5749, 1468-3288, 1468-3288
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!