Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis

ObjectiveBiological insights into the stepwise development and progression of colorectal cancer (CRC) are imperative to develop tailored approaches for early detection and optimal clinical management of this disease. Here, we aimed to dissect the transcriptional and immunologic alterations that acco...

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Veröffentlicht in:	Gut Jg. 72; H. 7; S. 1326 - 1339
Hauptverfasser:	Roelands, Jessica, van der Ploeg, Manon, Ijsselsteijn, Marieke E, Dang, Hao, Boonstra, Jurjen J, Hardwick, James C H, Hawinkels, Lukas J A C, Morreau, Hans, de Miranda, Noel F C C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England BMJ Publishing Group Ltd and British Society of Gastroenterology 01.07.2023 BMJ Publishing Group LTD BMJ Publishing Group
Schriftenreihe:	Original research
Schlagworte:	Biomarkers Cancer Cell Transformation, Neoplastic - genetics Colon Colorectal cancer Colorectal carcinoma colorectal neogenesis Colorectal Neoplasms - pathology Cytometry Dysplasia Endoscopy Epithelium Gene expression Gene Expression Profiling Genetic transformation Genomics Histocompatibility antigen HLA Humans immunogenetics Inflammation Macrophages Metastases Myeloid cells Patients Transcriptome Transcriptomics Tumorigenesis Tumors colorectal neogenesis immunogenetics gene expression
ISSN:	0017-5749, 1468-3288, 1468-3288
Online-Zugang:	Volltext
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