Age-related differences in glycaemic control, cardiovascular disease risk factors and treatment in patients with type 2 diabetes: a cross-sectional study from the Australian National Diabetes Audit

ObjectiveTo compare the glycaemic control and cardiovascular risk factor profiles of younger and older patients with type 2 diabetes. Cross-sectional analysis of data from the 2015 Australian National Diabetes Audit was undertaken.MethodsData were obtained from adults with type 2 diabetes presenting...

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Published in:BMJ open Vol. 8; no. 8; p. e020677
Main Authors: Nanayakkara, Natalie, Ranasinha, Sanjeeva, Gadowski, Adelle M, Davis, Wendy A, Flack, Jeffrey Ronald, Wischer, Natalie, Andrikopoulos, Sof, Zoungas, Sophia
Format: Journal Article
Language:English
Published: England BMJ Publishing Group LTD 01.08.2018
BMJ Publishing Group
Subjects:
Age
Age Factors
Australia - epidemiology
Blood Glucose - analysis
Blood pressure
Body mass index
Cardiology
Cardiovascular disease
Cross-Sectional Studies
Diabetes
Diabetes and Endocrinology
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - epidemiology
Dyslipidemias - epidemiology
Epidemiology
Female
Gender differences
Glycated Hemoglobin - analysis
Health risk assessment
Heart
Humans
Hypertension
Lipids
Male
Medical Audit
Middle Aged
Obesity
Obesity - epidemiology
Patients
Risk Factors
Smoking - epidemiology
Statistical analysis
Task forces
Variables
Women
Australia
epidemiology
general diabetes
general medicine (see internal medicine)
ISSN:2044-6055, 2044-6055
Online Access:Get full text
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Summary:ObjectiveTo compare the glycaemic control and cardiovascular risk factor profiles of younger and older patients with type 2 diabetes. Cross-sectional analysis of data from the 2015 Australian National Diabetes Audit was undertaken.MethodsData were obtained from adults with type 2 diabetes presenting to Australian secondary/tertiary diabetes centres. Logistic regression examined associations with glycated haemoglobin A1c (HbA1c) >7% (53 mmol/mol) and cardiovascular risk factors.ResultsData from 3492 patients were analysed. Mean (±SD) age was 62.9±12.5 years, mean diabetes duration 13.5±9.4 years and mean HbA1c 8.2%±1.8%. Mean HbA1c was 8.6%±2.1% and 8.0%±1.6% for the younger (<60 years) and older subgroups (≥60 years), respectively (p<0.001). The adjusted OR (aOR) of HbA1c above >7.0% was 1.5 times higher (95% CI 1.22 to 1.84) for younger patients compared with older patients after adjustment for gender, smoking, diabetes duration, renal function and body mass index. Younger patients were also more likely to have dyslipidaemia (aOR 2.02, 95% CI 1.53 to 2.68; p<0.001), be obese (aOR 1.25, 95% CI 1.05 to 1.49; p<0.001) and be current smokers (aOR 2.13 95% CI 1.64 to 2.77; p<0.001) than older patients.ConclusionsYounger age was associated with poorer glycaemic control and adverse cardiovascular risk factor profiles. It is imperative to optimise and monitor treatment in order to improve long-term outcomes.
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ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2017-020677