Thyroid Hormones, Metabolic Syndrome and Its Components

Metabolic syndrome is a clustering of various metabolic parameters, which include diabetes, low high-density lipoprotein cholesterol, elevated triglycerides, abdominal obesity, and hypertension. It has merged as a worldwide epidemic and a major public health care concern. However, due to the differe...

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Published in:Endocrine, metabolic & immune disorders drug targets Vol. 17; no. 1; p. 56
Main Authors: Delitala, Alessandro P, Fanciulli, Giuseppe, Pes, Giovanni M, Maioli, Margherita, Delitala, Giuseppe
Format: Journal Article
Language:English
Published: United Arab Emirates 01.01.2017
Subjects:
Cardiovascular Diseases - blood
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - epidemiology
Humans
Hypothyroidism - blood
Hypothyroidism - diagnosis
Hypothyroidism - epidemiology
Metabolic Syndrome - blood
Metabolic Syndrome - diagnosis
Metabolic Syndrome - epidemiology
Obesity - blood
Obesity - diagnosis
Obesity - epidemiology
Risk Factors
Thyroid Hormones - blood
cardiovascular risk
thyroid hormone
Metabolic syndrome
subclinical hypothyroidism
obesity
ISSN:2212-3873, 2212-3873
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Summary:Metabolic syndrome is a clustering of various metabolic parameters, which include diabetes, low high-density lipoprotein cholesterol, elevated triglycerides, abdominal obesity, and hypertension. It has merged as a worldwide epidemic and a major public health care concern. However, due to the different criteria used for the assessment, the frequency of metabolic syndrome in the general population is variable but it is more common in the older people. Metabolic syndrome is closely linked to cardiovascular risk and increases cardiovascular outcomes and all-cause mortality. Recent evidences showed that alterations of the thyroid function could have an impact on the components of the metabolic syndrome, suggesting that thyroid hormones have a variety of effects on energy homeostasis, lipid and glucose metabolism, and blood pressure. In this review, we summarize available data on the action of thyroid hormone on the components of metabolic syndrome.
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ISSN:2212-3873
2212-3873
DOI:10.2174/1871530317666170320105221