Absence of genetic linkage of chromosome 5q31 with asthma and atopy in the general population

BACKGROUND: Clinical asthma is associated with increased serum total immunoglobulin E (IgE), atopy (skin prick test positivity to common aeroallergens), and bronchial hyperreactivity (BHR) to non-specific stimuli (positive methacholine challenge test). A region on chromosome 5q31-33 has been linked...

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Bibliographic Details
Published in:	Thorax Vol. 52; no. 9; pp. 816 - 817
Main Authors:	Kamitani, A, Wong, Z Y, Dickson, P, van Herwerden, L, Raven, J, Forbes, A B, Abramson, M J, Walters, E H, Harrap, S B
Format:	Journal Article
Language:	English
Published:	London BMJ 01.09.1997 BMJ Publishing Group LTD BMJ Group
Subjects:	Adult Alleles Asthma - genetics Biological and medical sciences Bronchial Hyperreactivity - genetics Chromosomes, Human, Pair 5 - genetics Chronic obstructive pulmonary disease, asthma Genetic Linkage Genetic Markers Humans Hypersensitivity - genetics Medical sciences Microsatellite Repeats Pneumology Human Allergy Immunopathology Genetic inheritance Linkage Respiratory disease Genetics Chromosome 5 Obstructive pulmonary disease Asthma Atopy
ISSN:	0040-6376, 1468-3296
Online Access:	Get full text
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