Quantitative lung T cell responses aid the rapid diagnosis of pulmonary tuberculosis

Background:The diagnosis of smear-negative pulmonary tuberculosis (TB) is problematic. There are limited data on the profile of alveolar TB antigen-specific T cells, and their utility for the rapid immunodiagnosis of pulmonary TB is unclear.Methods:Antigen-specific interferon γ (IFNγ) responses to t...

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Bibliographic Details
Published in:	Thorax Vol. 64; no. 10; pp. 847 - 853
Main Authors:	Dheda, K, van Zyl-Smit, R N, Meldau, R, Meldau, S, Symons, G, Khalfey, H, Govender, N, Rosu, V, Sechi, L A, Maredza, A, Semple, P, Whitelaw, A, Wainwright, H, Badri, M, Dawson, R, Bateman, E D, Zumla, A
Format:	Journal Article
Language:	English
Published:	London BMJ Publishing Group Ltd and British Thoracic Society 01.10.2009 BMJ Publishing Group BMJ Publishing Group LTD
Subjects:	Adult Antigens Antigens, Bacterial - metabolism Bacterial diseases Bacterial diseases of the respiratory system Bacteriological Techniques - methods Biological and medical sciences Biopsy Bronchoalveolar Lavage Fluid - immunology Cardiology. Vascular system Drug resistance Enzyme-Linked Immunosorbent Assay Female Histology HIV Human bacterial diseases Human immunodeficiency virus Humans Infections Infectious diseases Interferon-gamma - metabolism Lavage Lymphocytes Male Medical sciences Microscopy Mycobacterium tuberculosis - immunology Patients Pneumology T-Lymphocytes - immunology Tuberculosis Tuberculosis and atypical mycobacterial infections Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - immunology South Africa Cape Town South Africa Lung disease Respiratory disease Lung Pulmonary tuberculosis Cellular immunity Mycobacterial infection Infection Bacteriosis Anesthesia Circulatory system Diagnosis Cardiology Quantitative analysis
ISSN:	0040-6376, 1468-3296, 1468-3296
Online Access:	Get full text
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