Physical activity and body mass related to catch-up lung function growth in childhood: a population-based accelerated cohort study

ObjectiveThe existence of catch-up lung function growth and its predictors is uncertain. We aimed to identify lung function trajectories and their predictors in a population-based birth cohort.MethodsWe applied group-based trajectory modelling to z-scores of forced expiratory volume in 1 second (zFE...

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Veröffentlicht in:Thorax Jg. 79; H. 8; S. 762 - 769
Hauptverfasser: Koch, Sarah, Peralta, Gabriela Prado, Carsin, Anne-Elie, Abellan, Alicia, Roda, Celine, Torrent, Maties, Iñiguez, Carmen, Ballester, Ferran, Ferrero, Amparo, Zabaleta, Carlos, Lertxundi, Aitana, Guxens, Mònica, Vrijheid, Martine, Sunyer, Jordi, Casas, Maribel, Garcia-Aymerich, Judith
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England BMJ Publishing Group Ltd and British Thoracic Society 01.08.2024
BMJ Publishing Group LTD
Schlagworte:
Adolescent
Age
Asthma
Birth Cohort
Body Mass Index
Child
Child development
Child Development - physiology
Child, Preschool
Childhood
Childrens health
Chronic obstructive pulmonary disease
COPD epidemiology
Eczema
Exercise
Exercise - physiology
Female
Forced Expiratory Volume - physiology
Health care
Health risks
Humans
Investigations
Longitudinal studies
Lung - growth & development
Lung - physiology
Lungs
Male
Multiple births
Population-based studies
Pregnancy
Preschool children
Regression analysis
Respiratory diseases
Respiratory epidemiology
Rhinitis
Smoking
Spirometry
Tobacco smoke
Vital Capacity - physiology
COPD epidemiology
Exercise
ISSN:0040-6376, 1468-3296, 1468-3296
Online-Zugang:Volltext
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Zusammenfassung:ObjectiveThe existence of catch-up lung function growth and its predictors is uncertain. We aimed to identify lung function trajectories and their predictors in a population-based birth cohort.MethodsWe applied group-based trajectory modelling to z-scores of forced expiratory volume in 1 second (zFEV1) and z-scores of forced vital capacity (zFVC) from 1151 children assessed at around 4, 7, 9, 10, 11, 14 and 18 years. Multinomial logistic regression models were used to test whether potential prenatal and postnatal predictors were associated with lung function trajectories.ResultsWe identified four lung function trajectories: a low (19% and 19% of the sample for zFEV1 and zFVC, respectively), normal (62% and 63%), and high trajectory (16% and 13%) running in parallel, and a catch-up trajectory (2% and 5%) with catch-up occurring between 4 and 10 years. Fewer child allergic diseases and higher body mass index z-score (zBMI) at 4 years were associated with the high and normal compared with the low trajectories, both for zFEV1 and zFVC. Increased children’s physical activity during early childhood and higher zBMI at 4 years were associated with the catch-up compared with the low zFEV1 trajectory (relative risk ratios: 1.59 per physical activity category (1.03–2.46) and 1.47 per zBMI (0.97–2.23), respectively). No predictors were identified for zFVC catch-up growth.ConclusionWe found three parallel-running and one catch-up zFEV1 and zFVC trajectories, and identified physical activity and body mass at 4 years as predictors of zFEV1 but not zFVC catch-up growth.
Bibliographie:Original research
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0040-6376
1468-3296
1468-3296
DOI:10.1136/thorax-2022-219666