Fucosyltransferase 2 (FUT2) non-secretor status and blood group B are associated with elevated serum lipase activity in asymptomatic subjects, and an increased risk for chronic pancreatitis: a genetic association study

Objective Serum lipase activities above the threefold upper reference limit indicate acute pancreatitis. We investigated whether high lipase activity—within the reference range and in the absence of pancreatitis—are associated with genetic single nucleotide polymorphisms (SNP), and whether these ide...

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Bibliographic Details
Published in:	Gut Vol. 64; no. 4; pp. 646 - 656
Main Authors:	Weiss, Frank Ulrich, Schurmann, Claudia, Guenther, Annett, Ernst, Florian, Teumer, Alexander, Mayerle, Julia, Simon, Peter, Völzke, Henry, Radke, Dörte, Greinacher, Andreas, Kuehn, Jens-Peter, Zenker, Martin, Völker, Uwe, Homuth, Georg, Lerch, Markus M
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group LTD 01.04.2015
Subjects:	ABO Blood-Group System - physiology Adult Aged Aged, 80 and over Antigens Blood groups Consent Enzymes Female Fucosyltransferases - physiology Galactoside 2-alpha-L-fucosyltransferase Genetic Association Studies Genome-Wide Association Study Genomes Humans Lipase - blood Male Middle Aged Oils & fats Pancreatic cancer Pancreatitis, Chronic - epidemiology Pancreatitis, Chronic - genetics Polymorphism, Single Nucleotide Population Risk Assessment Rodents Studies Young Adult Pancreatic Enzymes Chronic Pancreatitis Linkage Analysis Glycosyltransferases Genetic Polymorphisms
ISSN:	0017-5749, 1468-3288, 1468-3288
Online Access:	Get full text
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