549 Characterizing double positive T cells in the tumor microenvironment: a tale of promiscuous cell fates

BackgroundCD4 and CD8 T cells are genetically and functionally distinct cell subsets of the adaptive immune system that play pivotal roles in immune surveillance and disease control. During development in the thymus, transcription factors ThPOK and Runx3 regulate the differentiation and maturation o...

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Vydané v:	Journal for immunotherapy of cancer Ročník 8; číslo Suppl 3; s. A333 - A334
Hlavní autori:	Schad, Sara, Chow, Andrew, Pan, Heng, Mangarin, Levi, Zappasodi, Roberta, Gigoux, Mathieu, Redmond, David, Hirschhorn-Cymerman, Daniel, Budhu, Sadna, Zhong, Hong, Yang, Xia, Elemento, Olivier, Wolchok, Jedd, Merghoub, Taha
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BMJ Publishing Group LTD 01.11.2020 BMJ Publishing Group
Predmet:	Antigens Antiviral drugs Cytotoxicity Immunotherapy Kidney cancer Lymphocytes Melanoma Tumors Urological cancer
ISSN:	2051-1426
On-line prístup:	Získať plný text
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