Evolutionary Dynamics of Non-Coding Regions in Pancreatic Ductal Adenocarcinoma

Abstract While the non-coding genome appears to play a role, the dynamic nature of noncoding alterations with respect to clonal progression of solid tumors remains unexplored. To address this gap in knowledge we performed multiregional whole genome sequencing and clonal analysis to elucidate the evo...

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Vydané v:	bioRxiv
Hlavní autori:	Hayashi, Akimasa, Yu-Jui, Ho, Makohon-Moore, Alvin P, Zucker, Amanda, Hong, Jungeui, Reiter, Johannes G, Huang, Jinlong, Zhang, Lance, Attiyeh, Marc A, Baez, Priscilla, Kappagantula, Rajya, Melchor, Jerry P, Eileen M O’reilly, Socci, Nicholas D, Oki, Shinya, Lowe, Scott W, Iacobuzio-Donahue, Christine A
Médium:	Paper
Jazyk:	English Japanese
Vydavateľské údaje:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 12.09.2020 Cold Spring Harbor Laboratory
Vydanie:	1.1
Predmet:	Adenocarcinoma Cancer Biology Deoxyribonucleic acid DNA Genomes Pancreatic cancer Solid tumors Whole genome sequencing
ISSN:	2692-8205, 2692-8205
On-line prístup:	Získať plný text
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