Quantifying B-cell Clonal Diversity In Repertoire Data

The adaptive immune system has the extraordinary ability to produce a broad range of immunoglobulins that can bind a wide variety of antigens. During adaptive immune responses, activated B~cells proliferate and undergo somatic hypermutation in their B-cell receptor (BCR) genes, resulting in clonal g...

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Vydané v:	bioRxiv
Hlavní autori:	Pelissier, Aurelien, Luo, Siyuan, Stratigopoulou, Maria, Guikema, Jeroen, Maria Rodriguez Martinez
Médium:	Paper
Jazyk:	English
Vydavateľské údaje:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 18.12.2022 Cold Spring Harbor Laboratory
Vydanie:	1.2
Predmet:	Antigens B-cell receptor Bioinformatics Immune response Immunoglobulins Lymphocytes B Next-generation sequencing Somatic hypermutation
ISSN:	2692-8205, 2692-8205
On-line prístup:	Získať plný text
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