Quantifying B-cell Clonal Diversity In Repertoire Data

The adaptive immune system has the extraordinary ability to produce a broad range of immunoglobulins that can bind a wide variety of antigens. During adaptive immune responses, activated B~cells proliferate and undergo somatic hypermutation in their B-cell receptor (BCR) genes, resulting in clonal g...

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Bibliographic Details
Published in:	bioRxiv
Main Authors:	Pelissier, Aurelien, Luo, Siyuan, Stratigopoulou, Maria, Guikema, Jeroen, Maria Rodriguez Martinez
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 18.12.2022 Cold Spring Harbor Laboratory
Edition:	1.2
Subjects:	Antigens B-cell receptor Bioinformatics Immune response Immunoglobulins Lymphocytes B Next-generation sequencing Somatic hypermutation
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
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