Cellular Peptidases in Immune Functions and Diseases 2

Of the many special roles played by proteolytic enzymes in immune reactions, this study addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane pepti...

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Bibliographic Details
Main Authors: Langner, Jürgen, Ansorge, Siegfried
Format: eBook
Language:English
Published: Boston, MA Springer 2000
Springer US
Edition:1
Series:Advances in Experimental Medicine and Biology
Subjects:
Biochemistry
Biochemistry, general
Biomedical and Life Sciences
Biomedicine
Congresses
Immunology
Medical Biochemistry
Oncology
Peptidase
Rheumatology
ISBN:0306463830, 9780306463839, 1475786492, 9781475786484, 9781475786491, 1475786484
ISSN:0065-2598
Online Access:Get full text
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Summary:Of the many special roles played by proteolytic enzymes in immune reactions, this study addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a useful feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.
ISBN:0306463830
9780306463839
1475786492
9781475786484
9781475786491
1475786484
ISSN:0065-2598
DOI:10.1007/b112039