Pharmacokinetics of first-line tuberculosis drugs in Tanzanian patients

East Africa has a high tuberculosis (TB) incidence and mortality, yet there are very limited data on exposure to TB drugs in patients from this region. We therefore determined the pharmacokinetic characteristics of first-line TB drugs in Tanzanian patients using intensive pharmacokinetic sampling. I...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy Jg. 57; H. 7; S. 3208
Hauptverfasser:	Tostmann, Alma, Mtabho, Charles M, Semvua, Hadija H, van den Boogaard, Jossy, Kibiki, Gibson S, Boeree, Martin J, Aarnoutse, Rob E
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2013
Schlagworte:	Adult Antitubercular Agents - blood Antitubercular Agents - pharmacokinetics Antitubercular Agents - therapeutic use Ethambutol - blood Ethambutol - pharmacokinetics Ethambutol - therapeutic use Female Humans Isoniazid - blood Isoniazid - pharmacokinetics Isoniazid - therapeutic use Male Pyrazinamide - blood Pyrazinamide - pharmacokinetics Pyrazinamide - therapeutic use Rifampin - blood Rifampin - pharmacokinetics Rifampin - therapeutic use Tanzania Treatment Outcome Tuberculosis, Pulmonary - drug therapy Tanzania
ISSN:	1098-6596, 1098-6596
Online-Zugang:	Weitere Angaben
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