Pharmacokinetics of first-line tuberculosis drugs in Tanzanian patients

East Africa has a high tuberculosis (TB) incidence and mortality, yet there are very limited data on exposure to TB drugs in patients from this region. We therefore determined the pharmacokinetic characteristics of first-line TB drugs in Tanzanian patients using intensive pharmacokinetic sampling. I...

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Vydané v:	Antimicrobial agents and chemotherapy Ročník 57; číslo 7; s. 3208
Hlavní autori:	Tostmann, Alma, Mtabho, Charles M, Semvua, Hadija H, van den Boogaard, Jossy, Kibiki, Gibson S, Boeree, Martin J, Aarnoutse, Rob E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.07.2013
Predmet:	Adult Antitubercular Agents - blood Antitubercular Agents - pharmacokinetics Antitubercular Agents - therapeutic use Ethambutol - blood Ethambutol - pharmacokinetics Ethambutol - therapeutic use Female Humans Isoniazid - blood Isoniazid - pharmacokinetics Isoniazid - therapeutic use Male Pyrazinamide - blood Pyrazinamide - pharmacokinetics Pyrazinamide - therapeutic use Rifampin - blood Rifampin - pharmacokinetics Rifampin - therapeutic use Tanzania Treatment Outcome Tuberculosis, Pulmonary - drug therapy Tanzania
ISSN:	1098-6596, 1098-6596
On-line prístup:	Zistit podrobnosti o prístupe
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