Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria

Pyrimethamine-sulfadoxine, the first choice for uncomplicated falciparum malaria in Africa, exerts strong selection pressure for resistance because of its slow elimination. It is likely that resistance will emerge rapidly, and there is no widely affordable replacement. Chlorproguanil-dapsone is chea...

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Bibliographic Details
Published in:	Antimicrobial agents and chemotherapy Vol. 41; no. 10; p. 2261
Main Authors:	Amukoye, E, Winstanley, P A, Watkins, W M, Snow, R W, Hatcher, J, Mosobo, M, Ngumbao, E, Lowe, B, Ton, M, Minyiri, G, Marsh, K
Format:	Journal Article
Language:	English
Published:	United States 01.10.1997
Subjects:	Antimalarials - therapeutic use Child Child, Preschool Dapsone - therapeutic use Double-Blind Method Drug Combinations Drug Resistance Female Hemoglobins - metabolism Humans Infant Malaria, Falciparum - blood Malaria, Falciparum - drug therapy Malaria, Falciparum - parasitology Male Proguanil - analogs & derivatives Proguanil - therapeutic use Pyrimethamine - therapeutic use Sulfadoxine - therapeutic use
ISSN:	0066-4804
Online Access:	Get more information
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