Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

The incremental value of polygenic risk scores in addition to well-established risk prediction models for coronary artery disease (CAD) is uncertain. To examine whether a polygenic risk score for CAD improves risk prediction beyond pooled cohort equations. Observational study of UK Biobank participa...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	JAMA : the journal of the American Medical Association Ročník 323; číslo 7; s. 636
Hlavní autori:	Elliott, Joshua, Bodinier, Barbara, Bond, Tom A, Chadeau-Hyam, Marc, Evangelou, Evangelos, Moons, Karel G M, Dehghan, Abbas, Muller, David C, Elliott, Paul, Tzoulaki, Ioanna
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 18.02.2020
Predmet:	Adult Aged Case-Control Studies Coronary Artery Disease - genetics Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Male Middle Aged Multifactorial Inheritance Predictive Value of Tests Risk Risk Assessment - methods ROC Curve
ISSN:	1538-3598, 1538-3598
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!