Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation

A large metabolomics study was performed on 600 plasma samples taken at four time points before and after a single intake of a high fat test meal by obese and lean subjects. All samples were analyzed by a liquid chromatography-mass spectrometry (LC-MS) lipidomic method for metabolic profiling. A pra...

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Bibliographic Details

Published in:	Analytical chemistry (Washington) Vol. 78; no. 2; p. 567
Main Authors:	Bijlsma, Sabina, Bobeldijk, Ivana, Verheij, Elwin R, Ramaker, Raymond, Kochhar, Sunil, Macdonald, Ian A, van Ommen, Ben, Smilde, Age K
Format:	Journal Article
Language:	English
Published:	United States 15.01.2006
Subjects:	Chromatography, Liquid Data Interpretation, Statistical Dietary Fats - administration & dosage Dietary Fats - blood Europe Humans Least-Squares Analysis Lipids - blood Mass Spectrometry Obesity - blood Postprandial Period - physiology Europe
ISSN:	0003-2700
Online Access:	Get more information
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