Modular One-Pot Strategy for the Synthesis of Heterobivalent Tracers

Bivalent ligands, i.e., molecules having two ligands covalently connected by a linker, have been gathering attention since the first description of their pharmacological potential in the early 80s. However, their synthesis, particularly of labeled heterobivalent ligands, can still be cumbersome and...

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Bibliographic Details
Published in:	ACS medicinal chemistry letters Vol. 14; no. 5; pp. 636 - 644
Main Authors:	Bailly, Thibaud, Bodin, Sacha, Goncalves, Victor, Denat, Franck, Morgat, Clement, Prignon, Aurelie, Valverde, Ibai E.
Format:	Journal Article
Language:	English
Published:	WASHINGTON Amer Chemical Soc 11.05.2023
Subjects:	Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology PROSTATE Heterobivalent ligands AVIDITY CXCR4 Drug delivery PEPTIDE RECEPTORS ANTAGONIST BIVALENT LIGANDS IN-VITRO AFFINITY SPACER LENGTH Bioconjugation OPIOID AGONIST Click chemistry Radiopharmaceuticals BINDING
ISSN:	1948-5875, 1948-5875
Online Access:	Get more information
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