Dynamic behavior of P53-Mdm2-Wip1 gene regulatory network under the influence of time delay and noise

The tumor suppressor protein P53 can regulate the cell cycle, thereby preventing cell abnormalities. In this paper, we study the dynamic characteristics of the P53 network under the influence of time delay and noise, including stability and bifurcation. In order to study the influence of several fac...

Full description

Bibliographic Details

Published in:	Mathematical biosciences and engineering : MBE Vol. 20; no. 2; pp. 2321 - 2347
Main Authors:	Luo, LanJiang, Liu, Haihong, Yan, Fang
Format:	Journal Article
Language:	English
Published:	United States AIMS Press 01.01.2023
Subjects:	bifurcation Computer Simulation Gene Regulatory Networks noise oscillation p53 network Protein Phosphatase 2C Proto-Oncogene Proteins c-maf time delay Tumor Suppressor Protein p53 - metabolism noise oscillation P53 network bifurcation time delay
ISSN:	1551-0018, 1551-0018
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!