Particles for multiplexed analysis in solution: detection and identification of striped metallic particles using optical microscopy
In this report, we present data demonstrating that cylindrical metallic particles, with various submicrometer striping patterns, may be readily distinguished in an optical microscope. Accurate particle identification is discussed relative to synthesis reproducibility and the limitations of optical m...
Gespeichert in:
| Veröffentlicht in: | Analytical chemistry (Washington) Jg. 74; H. 10; S. 2240 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
United States
15.05.2002
|
| Schlagworte: | |
| ISSN: | 0003-2700 |
| Online-Zugang: | Weitere Angaben |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | In this report, we present data demonstrating that cylindrical metallic particles, with various submicrometer striping patterns, may be readily distinguished in an optical microscope. Accurate particle identification is discussed relative to synthesis reproducibility and the limitations of optical microscopes. Results from a library of these particles, of which over 100 different striping patterns have been produced, are presented. For these particles, made with Au and Ag stripes, more than 70 patterns may be identified with greater than 90% accuracy. The ability to chemically modify the surface of these particles, making them useful for bioanalytical measurements, is also demonstrated. Finally, we discuss improvements in our manufacturing and identification processes that will lead to both larger numbers of striping patterns and improved identification accuracy. |
|---|---|
| AbstractList | In this report, we present data demonstrating that cylindrical metallic particles, with various submicrometer striping patterns, may be readily distinguished in an optical microscope. Accurate particle identification is discussed relative to synthesis reproducibility and the limitations of optical microscopes. Results from a library of these particles, of which over 100 different striping patterns have been produced, are presented. For these particles, made with Au and Ag stripes, more than 70 patterns may be identified with greater than 90% accuracy. The ability to chemically modify the surface of these particles, making them useful for bioanalytical measurements, is also demonstrated. Finally, we discuss improvements in our manufacturing and identification processes that will lead to both larger numbers of striping patterns and improved identification accuracy.In this report, we present data demonstrating that cylindrical metallic particles, with various submicrometer striping patterns, may be readily distinguished in an optical microscope. Accurate particle identification is discussed relative to synthesis reproducibility and the limitations of optical microscopes. Results from a library of these particles, of which over 100 different striping patterns have been produced, are presented. For these particles, made with Au and Ag stripes, more than 70 patterns may be identified with greater than 90% accuracy. The ability to chemically modify the surface of these particles, making them useful for bioanalytical measurements, is also demonstrated. Finally, we discuss improvements in our manufacturing and identification processes that will lead to both larger numbers of striping patterns and improved identification accuracy. In this report, we present data demonstrating that cylindrical metallic particles, with various submicrometer striping patterns, may be readily distinguished in an optical microscope. Accurate particle identification is discussed relative to synthesis reproducibility and the limitations of optical microscopes. Results from a library of these particles, of which over 100 different striping patterns have been produced, are presented. For these particles, made with Au and Ag stripes, more than 70 patterns may be identified with greater than 90% accuracy. The ability to chemically modify the surface of these particles, making them useful for bioanalytical measurements, is also demonstrated. Finally, we discuss improvements in our manufacturing and identification processes that will lead to both larger numbers of striping patterns and improved identification accuracy. |
| Author | Walton, Ian D Norton, Scott M Gupta, Dimpy He, Lin Freeman, R Griffith Balasingham, Arjuna Natan, Michael J Oviso, Jr, Dominador F Raju, Paul A |
| Author_xml | – sequence: 1 givenname: Ian D surname: Walton fullname: Walton, Ian D organization: SurroMed, Inc., Mountain View, California 94043, USA – sequence: 2 givenname: Scott M surname: Norton fullname: Norton, Scott M – sequence: 3 givenname: Arjuna surname: Balasingham fullname: Balasingham, Arjuna – sequence: 4 givenname: Lin surname: He fullname: He, Lin – sequence: 5 givenname: Dominador F surname: Oviso, Jr fullname: Oviso, Jr, Dominador F – sequence: 6 givenname: Dimpy surname: Gupta fullname: Gupta, Dimpy – sequence: 7 givenname: Paul A surname: Raju fullname: Raju, Paul A – sequence: 8 givenname: Michael J surname: Natan fullname: Natan, Michael J – sequence: 9 givenname: R Griffith surname: Freeman fullname: Freeman, R Griffith |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/12038747$$D View this record in MEDLINE/PubMed |
| BookMark | eNo9ULtOxDAQdHGIe0DBDyBXdIG144sdOnTiJSFBAXW02A4ycuwQO4Kr-XECHDQ7-5iZlWZJZiEGS8gRg1MGnJ2hBg4gy_cZWQBAWXAJMCfLlF4BGANW7ZM541AqKeSCfD7gkJ32NtE2DrQbfXa9tx_WUAzot8kl6gJN0Y_ZxXBOjc1Wf7fT3VBnbMiudRp_VrGlKQ-un9Sdzei907T_fzAmF15o7KcRPe2cHmLSsd8ekL0WfbKHO1yRp6vLx81NcXd_fbu5uCtQSJ4LsQaNQinGajsV1BUyQFnVKEHUaBQvq1YpVdtKYWmYAVEJRCsqQKamcFbk5Ne3H-LbaFNuOpe09R6DjWNqJJOlWnM-EY93xPG5s6bpB9fhsG3-YuNfSolwsg |
| CitedBy_id | crossref_primary_10_1039_b803807d crossref_primary_10_1002_anie_200504025 crossref_primary_10_1016_j_bios_2010_12_010 crossref_primary_10_1016_j_cap_2012_02_030 crossref_primary_10_1016_j_bios_2003_08_014 crossref_primary_10_2217_17435889_2_5_695 crossref_primary_10_2116_analsci_30_89 crossref_primary_10_1002_ange_200601104 crossref_primary_10_3390_ma12233908 crossref_primary_10_1002_wnan_19 crossref_primary_10_1016_j_bios_2014_12_023 crossref_primary_10_1002_elps_200700448 crossref_primary_10_1002_adma_200390105 crossref_primary_10_1002_wnan_96 crossref_primary_10_1002_smll_200600727 crossref_primary_10_1002_adma_202004734 crossref_primary_10_1063_1_2745438 crossref_primary_10_1002_ange_200600288 crossref_primary_10_1007_s12030_007_0003_5 crossref_primary_10_1039_b501146a crossref_primary_10_1109_LMAG_2016_2618781 crossref_primary_10_1385_NBT_1_4_327 crossref_primary_10_1002_anie_200600288 crossref_primary_10_1007_s00216_005_0225_0 crossref_primary_10_1016_j_cbpa_2008_08_027 crossref_primary_10_1021_cr0300789 crossref_primary_10_1007_s00216_008_2062_4 crossref_primary_10_1007_s10404_007_0240_x crossref_primary_10_2116_analsci_30_319 crossref_primary_10_1073_pnas_0236044100 crossref_primary_10_1155_2010_203756 crossref_primary_10_1364_AO_44_006285 crossref_primary_10_2217_nnm_09_92 crossref_primary_10_1016_j_bios_2012_07_013 crossref_primary_10_1039_b610085f crossref_primary_10_1016_j_actamat_2013_11_067 crossref_primary_10_1021_ja0658261 crossref_primary_10_1021_ja0637200 crossref_primary_10_1039_B814408G crossref_primary_10_1002_adma_200390089 crossref_primary_10_1002_smll_200701047 crossref_primary_10_1016_j_nano_2006_11_008 crossref_primary_10_1039_b903728d crossref_primary_10_1373_clinchem_2003_029850 crossref_primary_10_1002_adom_201400232 crossref_primary_10_1088_0957_4484_16_7_002 crossref_primary_10_1002_ange_200504025 crossref_primary_10_1002_cphc_200900377 crossref_primary_10_1021_ic0601384 crossref_primary_10_1002_anie_200601104 crossref_primary_10_1021_jp034139i crossref_primary_10_1016_j_aca_2013_08_039 crossref_primary_10_1016_j_cccn_2005_03_014 crossref_primary_10_1039_C9QM00607A crossref_primary_10_1016_j_jcis_2016_01_055 crossref_primary_10_1016_j_trac_2008_11_012 crossref_primary_10_1016_S0958_1669_02_00015_0 crossref_primary_10_1063_1_2162449 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1021/ac020073w |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Engineering Chemistry |
| ExternalDocumentID | 12038747 |
| Genre | Research Support, U.S. Gov't, Non-P.H.S Research Support, U.S. Gov't, P.H.S Journal Article |
| GrantInformation_xml | – fundername: NIDDK NIH HHS grantid: 1R43DK059077-01 |
| GroupedDBID | --- -DZ -~X .DC .GJ .K2 186 23M 3EH 3O- 4.4 53G 55A 5GY 5RE 5VS 6J9 6TJ 7~N 85S AABXI AAHBH AAUTI ABDEX ABHFT ABHMW ABJNI ABMVS ABOCM ABPPZ ABQRX ABUCX ACBEA ACGFO ACGFS ACGOD ACIWK ACJ ACKIV ACKOT ACNCT ACPRK ACPVT ACRPL ACS ADHLV ADNMO AEESW AENEX AEYZD AFEFF AFFDN AFFNX AFRAH AGXLV AHGAQ AIDAL ALMA_UNASSIGNED_HOLDINGS ANPPW ANTXH AQSVZ BAANH BKOMP CGR CS3 CUPRZ CUY CVF D0L EBS ECM ED~ EIF EJD F5P GGK GNL IH9 IHE JG~ KZ1 LG6 NHB NPM OHT P2P PQQKQ ROL RXW TAE TN5 UHB UI2 UKR VF5 VG9 VOH VQA VXZ W1F WH7 X6Y XOL XSW YIN YR5 YYP YZZ ZCA ZCG ZGI ~02 7X8 ABBLG ABLBI ADXHL AETEA AGQPQ |
| ID | FETCH-LOGICAL-a472t-450ca488119e811ac6a10a769a7049ad8236f8889e68a3d1d0464aae460a18102 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 105 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000175662100002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0003-2700 |
| IngestDate | Fri Jul 11 07:50:09 EDT 2025 Wed Feb 19 02:36:43 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 10 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-a472t-450ca488119e811ac6a10a769a7049ad8236f8889e68a3d1d0464aae460a18102 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 12038747 |
| PQID | 71738522 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_71738522 pubmed_primary_12038747 |
| PublicationCentury | 2000 |
| PublicationDate | 2002-05-15 |
| PublicationDateYYYYMMDD | 2002-05-15 |
| PublicationDate_xml | – month: 05 year: 2002 text: 2002-05-15 day: 15 |
| PublicationDecade | 2000 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Analytical chemistry (Washington) |
| PublicationTitleAlternate | Anal Chem |
| PublicationYear | 2002 |
| SSID | ssj0011016 |
| Score | 2.0551789 |
| Snippet | In this report, we present data demonstrating that cylindrical metallic particles, with various submicrometer striping patterns, may be readily distinguished... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 2240 |
| SubjectTerms | Diagnostic Imaging - standards Electronic Data Processing - instrumentation Electronic Data Processing - methods Electronic Data Processing - standards Metals - standards Microscopy - methods Nanotechnology Particle Size |
| Title | Particles for multiplexed analysis in solution: detection and identification of striped metallic particles using optical microscopy |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/12038747 https://www.proquest.com/docview/71738522 |
| Volume | 74 |
| WOSCitedRecordID | wos000175662100002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV07T8MwED4VigQMPMqrPD2wRk2cxHYQEkIVFQtVB5C6RW7soEo0CbS8Zv44PjcGFsTA4iWyEp3Pznd3n-8DOKWahUzR0BMizD2zExNPaK68SGdUqphyKn0rNsH7fTEcJoMGnLu7MEirdGeiPahVmWGOvIPVYmHAwkX16KFmFNZWawGNBWiGBsigT_Phdw0B41Knl4flVddXiAYdmfmYowtff8eV9v_SW__fl23AWo0ryeXcETahoYsWLHednFsLVn90HtyCj4FjxBGDWomjFb5pRWTdpoSMC-Ic84woPbOkrcI8V2SsapKRXVdS5gTlPyoze6INmn8YZ6T6egFS6-9JWdmsOZkgAxDvwrxvw13v6rZ77dV6DJ6MOJ15UexjD3QRBIk2g8yYDHzJWSK5iTOkQu303ETUiWZChipQWDaVUkfMlwZI-HQHFouy0HtAmIximmNreMxoxmyUm8iKjgx-0MwfibANJ87WqbETFjFkocvnaeqs3Ybd-XKl1bwtRxpQLMVHfP_PuQewYkVdsAlrfAjN3Ox0fQRL2ctsPH06tm5kxv7g5hM5VdRX |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Particles+for+multiplexed+analysis+in+solution%3A+detection+and+identification+of+striped+metallic+particles+using+optical+microscopy&rft.jtitle=Analytical+chemistry+%28Washington%29&rft.au=Walton%2C+Ian+D&rft.au=Norton%2C+Scott+M&rft.au=Balasingham%2C+Arjuna&rft.au=He%2C+Lin&rft.date=2002-05-15&rft.issn=0003-2700&rft.volume=74&rft.issue=10&rft.spage=2240&rft_id=info:doi/10.1021%2Fac020073w&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0003-2700&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0003-2700&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0003-2700&client=summon |